Knox brings 20 years’ experience to the study and evaluation of social programs, with special expertise in how supports for low-income workers — particularly child support and financial incentives — affect families and children. She currently directs the Supporting Healthy Marriage project, a federally funded evaluation of interventions aimed at improving child well-being by strengthening the relationships of married couples. She also oversees the Next Generation project, a multidisciplinary initiative to study welfare reform programs' impacts on the well-being of children and families. Knox has direct knowledge of welfare systems, having been special assistant to the executive deputy commissioner for income maintenance in New York City’s Human Resources Administration, where her responsibilities included estimating the cost of welfare reform programs. The author of numerous reports and papers, Knox has a doctorate in public policy from Harvard University.